Title : Mpox in Urban Africa: A study of epidemiological dynamics and clinical presentations in the Limete health zone, Kinshasa, 2025
Abstract:
Introduction: This study aims to describe the epidemiological dynamics and clinical characteristics of Mpox cases in the Limete urban health zone (Kinshasa, DRC) in 2025, against the backdrop of a regional resurgence of the virus.
Methodology: A descriptive cross-sectional study was conducted among Mpox cases. Sociodemographic, clinical, geographic, and surveillance data were collected and analyzed.
Results: The results reveal a predominance of females (56%), a high proportion of young adults (ages 16–35, 58%), and a marked geographic concentration in Industrial Health Zone 3 (66% of cases). The most affected occupational groups were private-sector workers (42%) and students (26%). Clinically, the most common symptoms were fever (83%) and skin rashes, with a predominance of vesiculopustular lesions (93.9%). The majority of cases presented with between 25 and 100 lesions (72.6%), indicating moderate forms of the disease. Half of the cases were detected through active case finding, and 71% of investigations were conducted at home. Contact tracing was low (11%), and 97% of cases had no smallpox immunity or Mpox vaccination.
Conclusion: The study highlights atypical local dynamics of Mpox in Limete, influenced by sociocultural, occupational, and environmental factors. The clinical profile remains consistent with classic forms of the disease. These results underscore the importance of enhanced surveillance, improved vaccination coverage, and targeted interventions in urban slums to limit the spread of the virus.
Keywords: Epidemiological Dynamics, Clinical Presentation, Mpox
